The role of metal ions in biochemistry

Other metals like magnesium and copper act to stabilize the shapes of enzymes.

The role of metal ions in biochemistry

Selected References These references are in PubMed.

The role of metal ions in biochemistry

This may not be the complete list of references from this article. Jung C, Rothstein A. Arsenate uptake and release in relation to the inhibition of transport and glycolysis in yeast. Serum stimulation of phosphate uptake into 3T3 cells.

The tagging of red cells and plasma proteins with radioactive chromium. Distribution and valence state of radiochromium in intracellularly labeled Ehrlich mouse ascites carcinoma cells. Proc Soc Exp Biol Med.

The uptake and retention of chromium by cells. Chromate transport in human leukocytes. Sulphate transport by rat ileum. Effect of molybdate and other anions.

Molybdate and tungstate transfer by rat ileum.

However, there are some metal ions that are highly toxic in excessive amounts. Thus, the body exerts strict control to assure that only one or two free metal atoms are present inside an individual cell. The RNA World, Second Edition© Cold Spring Harbor Laboratory Press /99 12 The Role of Metal Ions in RNA Biochemistry Andrew L. Feig and Olke C. Uhlenbeck Department of Chemistry and Biochemistry. Metal ions are fundamental elements for the maintenance of lifespan of plants, animals and humans. Their substantial role in biological systems was recognized a long time ago. They are essential for the maintenance of life and their absence can cause growth disorders, severe .

Competitive inhibition by sulphate. The competition of molybdate and sulphate ions for a transport system in the ovine small intestine. Interactions of copper, molybdenum, and sulfate in ruminant nutrition. Active sulfate transport in Saccharomyces cerevisiae.

Transinhibition kinetics of the sulfate transport system of Penicillium notatum: Transport of molybdate by Clostridium pasteurianum. A binding site for sulfate and its relation to sulfate transport into Salmonella typhimurium.

Transition metal ion inhibition of enzyme-catalyzed phosphate ester displacement reactions.

The role of metal ions in biochemistry

J Am Chem Soc. Phosphoprotein phosphatase in bovine tracheal smooth muscle. Multiple fractions and multiple substrates. Possible transition-state analogs for ribonuclease. The complexes of uridine with oxovanadium IV ion and vanadium V ion.

Potent inhibition of dynein adenosinetriphosphatase and of the motility of cilia and sperm flagella by vanadate. Inhibition of dynein ATPase by vanadate, and its possible use as a probe for the role of dynein in cytoplasmic motility.

Biochem Biophys Res Commun. Inhibition of myosin ATPase by vanadate ion. Mechanistic and regulatory implications. Effect of vanadate on cardiac contraction and adenylate cyclase. Activation of adenylate cyclase by vanadate. Vanadate blocks cyclic AMP-induced stimulation of sodium and water transport in amphibian epithelia.

Activation of adenylate cyclase by molybdate. Evidence that dephosphorylation inactivates glucocorticoid receptors. Glucocorticoid receptor inactivation under cell-free conditions. Molybdate inhibition of glucocorticoid receptor inactivation and transformation. Evidence for a tyrosine residue at the active site of phosphoglucomutase and its interaction with vanadate.

The active site of 6-phosphogluconate dehydrogenase. A phosphate binding site and its surroundings. Inactivation of phosphorylase b by potassium ferrate, a new reactive analogue of the phosphate group.

A comparison of arsenate and vanadate as inhibitors or uncouplers of mitochondrial and glycolytic energy metabolism.BioMetals is the only established journal to feature the important role of metal ions in chemistry, biology, biochemistry, environmental science, and medicine.

BioMetals is an international, multidisciplinary journal singularly devoted to the rapid publication of the fundamental advances of both basic and applied research in this field.

Some such metal ions are K+, Cu+, Fe2+, Mg2+, Mn2+, Ca2+, Cu2+, Zn2+, Fe3+ etc, Common metal ions which play a function in enzyme action are mentioned below: – 1. Magnesium ions help the enzymes that catalyze the synthesis of oligosaccharides and proteins.

The RNA World, Second Edition© Cold Spring Harbor Laboratory Press /99 12 The Role of Metal Ions in RNA Biochemistry Andrew L.

Feig and Olke C. Uhlenbeck Department of Chemistry and Biochemistry. Metals such as iron, zinc, and copper all perform important roles in many of the enzymatic reactions that fuel the body’s metabolism.

For instance, ions such as Fe 2+ can bind to the hemoglobin and myoglobin protein to help transport oxygen to organs in the body. Importance of Metal Ions in Biochemistry Metal ions play a significant role in the biological systems especially when the ion has empty or half filled d-orbitals. They can positively and negatively affect metabolic processes.

Published: Wed, 03 May Metal ions are essential for living processes. Intra and inter cellular communications rest largely on the concentration gradients of potassium, sodium, calcium ions like calcium play a significant role in blood clotting and muscle contraction, magnesium ions help in photosynthesis.

The Role Of Material Ions In Biochemistry